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Graduate & Doctoral Nursing Research Guide

PubMed is a database of medical research maintained by the U.S. National Library of Medicine (NLM) at the National Institutes of Health (NIH). It includes articles from the MEDLINE database and PubMed Central which is a full text archive of articles from journals reviewed and selected by NLM for archiving.

One of PubMed's strengths is its flexibility in how you can search, however, this also makes it challenging to learn. The resources on this page will provide more details on how PubMed is organized to help you understand the "why" behind PubMed search strategies.

Automatic Term Mapping

A very important feature to know about PubMed is automatic term mapping.

The video below explains how this feature can be useful for lower stakes or novice searching but could negatively impact research such as dissertations or systematic reviews.

Levels of Filtering/Limiting

"How does using MeSH terms help to narrow my search results?"

Automatic Term mapping with Keywords
  • PubMed will automatically look for different variants of your keywords, including MeSH terms, expanding the number of articles returned. 
MeSH terms Options
  • [MeSH] with no restrictions/checkboxes:
    • PubMed will return any articles that include your selected term anywhere in the MeSH list, no matter how relevant to the article focus
  • [Majr] Heading:
    • Check the box for "Restrict to Major Heading"
    • PubMed will return articles where the selected MeSH term is the major focus of the article and will have an asterisk (*) on the term in the MeSH list of the article
  • [Mesh:NoExp]:
    • By checking the box, "Do not include MeSH terms found below this term in the MeSH hierarchy.", PubMed will NOT return articles with the MeSH terms that are underneath your selected term in the hierarchy. (This is not always available.) 
      • Example: Doing that for "Exercise" would exclude at least 10 more specific, but related terms such as walking
  • Sub-headings:
    • Used in combination with MeSH Headings to indicate that an article focuses on a specific aspect of a topic. 
      • For example, searching PubMed with pulmonary embolism/drug therapy will retrieve articles about drug therapies for pulmonary embolism. Pulmonary Embolism is the MeSH Heading and Drug Therapy is the Subheading.
    • Not all Subheadings can be attached to all MeSH Headings.

Tutorials by NLM & PubMed

While the Pace Library has many resources on searching, PubMed also provides access to a wide variety of tutorials and skills information to help educate about how the database functions.

Some tutorials we recommend starting with from the pages linked below:

  • Save searches and set email alerts
  • Using the Advanced Search Builder
  • Topic Searching in PubMed: Using the Medical Subject Headings (MeSH)
  • Phrase Searching in PubMed Tutorial

For a very detailed look into how PubMed works, this longer video (1.5 hours) explores many aspects of using the database. The description includes chapter links to different topics in the video for easy navigation.

PubMed vs MEDLINE

In the PubMed searching videos from the Pace Library, you will see a recommendation to include keywords AND controlled vocabulary in your search term strategy. The image below provides a visual explanation for that strategy.

Image of a large, dark blue circle with the following text inside: PubMed - Millions of reference to biomedicine and health literature, including all of MEDLINE. Includes new articles not yet fully indexed and publications that don't meet criteria for MEDLINE inclusion
Inside the large, dark blue circle is a smaller, light blue circle with the following text inside: MEDLINE - references to reputable journals selected by NIH, indexed by NLM Medical Subject Headings (MeSH)
White box at the bottom includes the following text: Caution - Applying ANY filters (other than date) to PubMed search results will limit search results to MEDLINE
Text next to the circles reads:
Why is it necessary to search by keyword as well as controlled vocabulary??
  • Keyword searches includes all of PubMed, not just MEDLINE
  • MeSH term searches include ONLY MEDLINE
  • Lag time in articles being indexed (assigned MeSH terms) by NLM
  • An indexer may fail to assign a relevant MeSH term to an article
  • Some journals are not indexed at all in MEDLINE